Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • DNA strands that form the helix have opposite orientations: one is in the direction 5′-3’y its complement in the 3′-5 ‘. The breaking of hydrogen bonds by heat, alkali or various chemical, produces the physical separation of the two strands of DNA in a process called denaturation. The heat denaturation is complete at 90 ° C and excess alkali pHs 11.3. In both cases the process is reversible, and the disappearance of the denaturing agent occurs renaturation of the molecule, ie the re-acquisition of lost-helical structure. ‘

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