Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • 2Embryonic development and morphogenesis of individual organs are common schemes based processes. In them, groups of undifferentiated cells, they initiate a series of complex interactions with internal and external signals, in order to establish patterns that direct cells to their subsequent proliferation, differentiation, coordinated morphological change and migration. This seemingly elementary, requires the integration of a series of activations and changes in the expression levels of a few basic genes. Two mechanisms are paramount in this general scheme: the proper control of temporal and spatial activation patterns of cell signaling, and the union of these patterns with cellular effectors that activate cellular responses in terms of gene activity or cell morphology. Read the rest of this entry »

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  • images9Procesos como el desarrollo embrionario, la angiogénesis, la cicatrización de heridas y la metástasis se basan en la migración celular, un complejo proceso regulado por múltiples rutas de señalización intracelular. Las integrinas y las GTPasas de bajo peso molecular de la familia Rho/Rac son algunos de los reguladores más importantes de este proceso. Read the rest of this entry »

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  • images55Understanding how cells organize and coordinate to form the tissues and organs in living organisms (morphogenesis) is a basic question in developmental biology. The morphogenesis requires a number of cellular processes that occur in a coordinated way in small groups of cells, including proliferation, migration, differentiation, growth, and reposicionamento rearrangement of cells within the tissue. The end result of all these processes is to form a body-dimensional structure-from the initial flat structure which are the first cells of the embryo. Read the rest of this entry »

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