Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • images53The processes of metastasis, associated with 90% of cancer deaths, are a series of chained steps where the primary tumor invades surrounding tissues and just spreading throughout the body. One of the first tissues to suffer metastasis are the lymph nodes surrounding the tumor. Manel Esteller’s group has recently published an article in PNAS conducted in the National Cancer Research Center (CNIO), explaining how tumor cells escape from their original location to the lymph nodes. Read the rest of this entry »

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  • images27The gene TARBP2 (TAR-RNA binding protein 2) is key to the production machinery of microRNA. These microRNAs are short strands of ribonucleic acid that regulate the intensity of the activity of other genes activated and deactivated, and active oncosupresora has been demonstrated in the past. In this study, conducted by a group of scientists from Finland, Portugal, USA and Spain, led by Manel Esteller, who led the group in the Cancer Epigenetics CNIO in Madrid and currently leads the Epigenetics of IDIBELL in Barcelona, have examined a number of cell lines of colorectal cancer, Read the rest of this entry »

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