Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • images24Structural Proteomics Group, Institute of Biomedicine of Valencia (CSIC) develops several years studies on the evolution and functional characteristics of different proteins from the venom of snakes, from the Mediterranean region. These proteins selectively block the function of cell surface receptors of the integrin family.

    Becoming available and genomic libraries of tissues and many different agencies. In this case, researchers in Valencia have been cloned and sequenced cDNA fragments of the venom-producing gland in Cerastes Viper and short disintegrins encoding and subunits of dimeric disintegrins. Read the rest of this entry »

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  • images65Reactive oxygen species (ROS) are highly toxic compounds produced in different metabolic processes. Normally, cells are capable of defending against such agents by the action of enzymes that degrade. However, increased ROS levels above the acceptable physiological limits leads to oxidative stress that may alter normal cellular functions and trigger cell death. In fact, oxidative stress in nerve cells is clearly implicated in the progression of various neurodegenerative diseases like Alzheimer’s and amyotrophic lateral sclerosis. In this sense, the study of the mechanisms that control oxidative cell death is an important part of current research of these diseases. Read the rest of this entry »

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