Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • 51The genetic model of cancer has led research in this field for decades, until Feinberg and Vogelstein (Johns Hopkins) described in 1983 an extensive loss of DNA methylation in tumor cells. With the results came the first evidence that epigenetic changes, heritable but outside the sequence, could make the cancer. The manifest skepticism that greeted the idea was in part due to the slow pace of progress in this field over the next fifteen years. Read the rest of this entry »

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  • 41Cancer is a genetic disease and epigenetics. The first thing is have ample evidence for years. Of the latter being generated every day more conclusive evidence. Demonstrate it has cost, despite the intense research carried out in this field and know the common feature in cancer cells provides the inactivation of tumor suppressor genes by mechanisms such as changes in the patterns of methylation of histones and DNA. Read the rest of this entry »

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