Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • 71085840Q: For twenty years you hammered out the problem of gene-specific causation and were finally able to identify genes associated with breast cancer, BRCA1 and then BRCA2. How are these discoveries affecting breast cancer research?

    DR. KING: I think the discoveries have had two different effects. First and most obviously they have an enormous, direct, clinical, and practical impact on women who carry these mutations. I think there’s no controversy now that BRCA1 and BRCA2 are the major breast cancer genes. Both BRCA1 and BRCA2 have a vast number of different protein-truncating mutations that abrogate their normal functions. But there still remains a great deal of controversy about just what risks for breast cancer and for ovarian cancer are associated with mutations in these genes. Read the rest of this entry »

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  • breast-cancer

    Q: You began studying breast cancer early in your career. How did you become interested in this line of inquiry and what made you think breast cancer could be inherited? Read the rest of this entry »

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