Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • the-mitofusin-2-in-mitochondrial-energizationThe mitofusin 2 (Mfn2) is a mitochondrial fusion protein whose expression decreased in skeletal muscle is related to processes such as obesity and type 2 diabetes and its deficiency decreases oxygen consumption, mitochondrial membrane potential and oxidation of glucose. In addition, he described an antiproliferative role in vascular disorders, and certain mutations in the Mfn2 gene, encoding this protein cause neurological disease Charcot-Marie-Tooth (CMT) type 2A, a hereditary sensorimotor neuropathy classified as rare.

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  • images25Brain development is a highly complex phenomenon that includes several sequential steps: determining regional specification of neuronal types, control of cell migration, formation of neural networks, etc. The correct orchestration of all elements and processes involved is essential for the development, organization and functioning of the brain. Among the agents that may be taken into account, a glycoprotein, reeling, has a prominent role for the proper organization and cellular architecture of the central nervous system. But, despite this prior knowledge, we know little of its role in the adult brain, although it could be involved in signaling processes linked to neurodegeneration. Read the rest of this entry »

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