Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • apoptotic-mechanisms-of-granzymes-in-ctl-lysisCytotoxic T lymphocytes (CTLs) eliminate virus-infected tumor cells or alloantigen through a lyric mechanism, which involves the secretion of a cytoplasmic granules containing cytotoxic proteins, perforin and granzymes, of which the two most important are granzyme A and granzyme B. Perforin interacts with cell membranes and allows the access of granzymes into the target cell, inducing cell death by apoptosis. Read the rest of this entry »

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