Molecular Staging

Molecular Staging is addressing this demand with a portfolio of products and services based on technologies that are transforming the detection and measurement of both proteins and nucleic acids.

  • Microarray Analysis and Data Management

    GEMTools™ software provides powerful tools for managing and analyzing the results of GEM™ microarray experiments. It utilizes a proprietary image recognition algorithm which interprets the scanned images of a processed GEM array. GEMTools software then compares those results against a library database to identify which genes were differentially expressed in the two cell samples and at what intensity. Read the rest of this entry »

    Comments Off on GEMTools
  • Fabricate Custom GEM arrays from provided cDNA clones. Database partners can also choose from  proprietary clone libraries.

    Once the Custom GEM array is built, you provide two samples per GEM for processing. We generate fluorescent labeled cDNA probes, hybridize them to the GEM arrays, scan the arrays, analyze the images, and provide complete data on gene expression. Data can be delivered in a standard format or in GEMTools software for further analysis and reporting. Read the rest of this entry »

    Comments Off on Custom GEM Development
  • liferay

    Microarray Data Management & Analysis

    LifeArray™ software manages and analyzes data resulting from microarray hybridization experiments. It includes a searchable database which can be loaded with microarray experimental results from a variety of formats. Read the rest of this entry »

    Comments Off on LifeArray
  • 71085840Q: For twenty years you hammered out the problem of gene-specific causation and were finally able to identify genes associated with breast cancer, BRCA1 and then BRCA2. How are these discoveries affecting breast cancer research?

    DR. KING: I think the discoveries have had two different effects. First and most obviously they have an enormous, direct, clinical, and practical impact on women who carry these mutations. I think there’s no controversy now that BRCA1 and BRCA2 are the major breast cancer genes. Both BRCA1 and BRCA2 have a vast number of different protein-truncating mutations that abrogate their normal functions. But there still remains a great deal of controversy about just what risks for breast cancer and for ovarian cancer are associated with mutations in these genes. Read the rest of this entry »

    Comments Off on Breast cancer breakthroughs